Abstract
Background:
Brain abscess are uncommon childhood infection. Brain abscess caused by Panton-Valentine Leukocidin positive Community acquired Methicillin Resistant Staphylococcal aureus have never been reported in the United Kingdom.
Case presentation:
We report a case of a previously well 11-month old boy of Indian origin who developed a parietal lobe abscess from PVL positive CA-MRSA.
Conclusion:
This case is one of the few described cases of brain abscess caused by PVL CA-MRSA in children. The unusual (insidious) presentation, the absence of a clear staphylococcal focus and the unexpected finding of a CA-MRSA in this patient highlight the challenges of managing such cases in clinical settings and the potential future risk to public health.
MeSH terms
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Anti-Bacterial Agents / therapeutic use
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Bacterial Toxins / isolation & purification*
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Brain Abscess / drug therapy
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Brain Abscess / microbiology
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Brain Abscess / pathology*
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Brain Abscess / surgery
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Community-Acquired Infections
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Exotoxins / isolation & purification*
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Humans
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Infant
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Leukocidins / isolation & purification*
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Male
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Methicillin-Resistant Staphylococcus aureus / drug effects
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Methicillin-Resistant Staphylococcus aureus / growth & development
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Methicillin-Resistant Staphylococcus aureus / pathogenicity
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Parietal Lobe / drug effects
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Parietal Lobe / microbiology
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Parietal Lobe / pathology*
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Parietal Lobe / surgery
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Staphylococcal Infections / drug therapy
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Staphylococcal Infections / microbiology
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Staphylococcal Infections / pathology*
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Staphylococcal Infections / surgery
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Treatment Outcome
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United Kingdom
Substances
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Anti-Bacterial Agents
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Bacterial Toxins
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Exotoxins
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Leukocidins
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Panton-Valentine leukocidin