[Fatal Panton-Valentine leukocidine-associated Staphylococcus aureus necrotizing pneumonia]

Ann Fr Anesth Reanim. 2014 Nov;33(11):596-9. doi: 10.1016/j.annfar.2014.09.003. Epub 2014 Oct 13.
[Article in French]

Abstract

Panton-Valentine leukocidin-producing Staphylococcus aureus necrotizing pneumonia is an unusual cause of community-acquired pneumonia associated with a high fatality rate. The specificities of its presentation must be known by the critical care doctor, in order to quickly make the diagnosis and start the right antibiotics and discuss adjunctive therapy with intravenous immunoglobin. Moreover, the management of close contacts (household and healthcare workers) of patient with such a pneumonia is not well-known. The present case report underlines the clinical presentation of this pneumonia, the specificities of its treatment, and specifies the management of close contacts.

Keywords: Cas contact; Contacts; Dépistage; Leucocidine de Panton-Valentine; Panton-Valentine leukocidin; Pneumonia; Pneumonie; Screening; Staphylococcus.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Adult
  • Anti-Bacterial Agents / therapeutic use
  • Bacterial Toxins / analysis
  • Bacterial Toxins / metabolism*
  • Case Management
  • Contact Tracing
  • Exotoxins / analysis
  • Exotoxins / metabolism*
  • Fatal Outcome
  • Female
  • Humans
  • Immunoglobulins, Intravenous / therapeutic use
  • Leukocidins / analysis
  • Leukocidins / metabolism*
  • Pneumonia, Staphylococcal / diagnosis
  • Pneumonia, Staphylococcal / drug therapy*
  • Pneumonia, Staphylococcal / microbiology*
  • Staphylococcus aureus / metabolism*

Substances

  • Anti-Bacterial Agents
  • Bacterial Toxins
  • Exotoxins
  • Immunoglobulins, Intravenous
  • Leukocidins
  • Panton-Valentine leukocidin