Evaluation of the efficiency of cefoxitin/cefepime combination against Enterobacteriaceae resistant to expanded-spectrum cephalosporins

Int J Antimicrob Agents. 2015 Jan;45(1):86-7. doi: 10.1016/j.ijantimicag.2014.10.001. Epub 2014 Oct 22.
No abstract available

Keywords: AmpC β-lactamase; Antibiotic resistance; Cefepime; Cefoxitin; ESBL; Gram-negative.

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animal Structures / microbiology
  • Animals
  • Bacterial Load
  • Cefepime
  • Cefoxitin / pharmacology
  • Cefoxitin / therapeutic use*
  • Cephalosporins / pharmacology
  • Cephalosporins / therapeutic use*
  • Disease Models, Animal
  • Drug Interactions
  • Drug Therapy, Combination
  • Enterobacteriaceae / drug effects*
  • Enterobacteriaceae / enzymology
  • Enterobacteriaceae / isolation & purification
  • Enterobacteriaceae Infections / drug therapy*
  • Enterobacteriaceae Infections / microbiology
  • Enterobacteriaceae Infections / pathology
  • Humans
  • Mice
  • Microbial Sensitivity Tests
  • Survival Analysis
  • Treatment Outcome
  • beta-Lactam Resistance*
  • beta-Lactamases / metabolism

Substances

  • Cephalosporins
  • Cefoxitin
  • Cefepime
  • beta-Lactamases