Abstract
Bacterial chromosomes are organized in stereotypical patterns that are faithfully and robustly regenerated in daughter cells. Two distinct spatial patterns were described almost a decade ago in our most tractable model organisms. In recent years, analysis of chromosome organization in a larger and more diverse set of bacteria and a deeper characterization of chromosome dynamics in the original model systems have provided a broader and more complete picture of both chromosome organization and the activities that generate the observed spatial patterns. Here, we summarize these different patterns highlighting similarities and differences and discuss the protein factors that help establish and maintain them.
Publication types
-
Research Support, N.I.H., Extramural
-
Research Support, Non-U.S. Gov't
-
Review
MeSH terms
-
Adenosine Triphosphatases / metabolism
-
Bacteria / genetics*
-
Bacteria / metabolism
-
Bacterial Proteins / chemistry
-
Bacterial Proteins / metabolism
-
Cell Cycle Proteins / chemistry
-
Cell Cycle Proteins / metabolism
-
Chromosomes, Bacterial / genetics*
-
Chromosomes, Bacterial / metabolism
-
DNA-Binding Proteins / metabolism
-
Genetic Structures*
-
Multiprotein Complexes / metabolism
-
Replication Origin
-
Telomere
Substances
-
Bacterial Proteins
-
Cell Cycle Proteins
-
DNA-Binding Proteins
-
DivIVA protein, bacteria
-
Multiprotein Complexes
-
chromosome partition proteins, bacterial
-
condensin complexes
-
Adenosine Triphosphatases