Electromechanical dissociation (EMD) is inconsistently defined in the literature. Our definition is the presence of discernible electrical complexes (excluding ventricular tachycardia and ventricular fibrillation) and the absence of palpable pulses. It has been noted that EMD may present with a variety of morphological complexes. It was the purpose of this study to categorize the electrical morphologic characteristics of patients presenting in EMD and to correlate morphology with patient outcome and response to therapy. From the 6-year period, January 1st, 1980 to December 31st, 1985, 503 evaluable adult patients presented to an urban paramedic system in non-traumatic, non-poisoned, cardiorespiratory arrest and were determined to be in EMD. The rhythm strips obtained from paramedics on all patients were retrospectively reviewed and were arbitrarily categorized in the following manner: Group 1, normal QRS width, isoelectric ST and normal appearing T-waves; Group 2A, atrial activity, widened QRS width (greater than or equal to 0.12 ms) or abnormal ST and/or T-waves (ST depression, elevation, slurring or T-wave inversion); Group 2B, same as Group 2A but without atrial activity; Group 3, essentially monophasic, slurred RST complexes. The respective initial distribution was Group 1, 147 (29%); Group 2A, 248 (49%); Group 2B, 60 (12%); Group 3, 48 (10%). The relative frequency of morphologies preceding the attainment of a pulse was as follows: Group 1, 30 (24%); Group 2A, 82 (65%); Group 2B, 8 (6%); Group 3, 6 (5%) (P less than or equal to 0.01 with no significant difference between Group 2B and 3).(ABSTRACT TRUNCATED AT 250 WORDS)