Catheter salvage in home infusion patients with central line-associated bloodstream infection

Daniel A Caroff; Anne H Norris; Sara Keller; Christopher Vinnard; Kristen E Zeitler; Jennifer Lukaszewicz; Kristine A Zborowski; Darren R Linkin; CDC Prevention Epicenters Program

doi:10.1016/j.ajic.2014.08.015

Catheter salvage in home infusion patients with central line-associated bloodstream infection

Am J Infect Control. 2014 Dec;42(12):1331-3. doi: 10.1016/j.ajic.2014.08.015. Epub 2014 Nov 25.

Authors

Daniel A Caroff¹, Anne H Norris², Sara Keller³, Christopher Vinnard⁴, Kristen E Zeitler⁵, Jennifer Lukaszewicz⁶, Kristine A Zborowski⁷, Darren R Linkin⁸; CDC Prevention Epicenters Program

Affiliations

¹ Division of Infectious Disease, Department of Medicine, Massachusetts General Hospital, Brigham and Women's Hospital, Harvard Medical School, Boston, MA. Electronic address: [email protected].
² Infectious Diseases Division, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.
³ Division of Infectious Diseases, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD.
⁴ Department of Medicine, Drexel University College of Medicine, Philadelphia, PA.
⁵ Department of Pharmacy, Tampa General Hospital, Tampa, FL.
⁶ Department of Pharmacy, University of Pennsylvania, Philadelphia, PA.
⁷ Penn Home Care and Hospice Services, Penn Home Infusion Therapy, King of Prussia, PA.
⁸ Infectious Diseases Division, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA; Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.

Abstract

In a retrospective study of home infusion patients with central line-associated bloodstream infection, use of a central venous port, cancer diagnosis, and absence of systemic inflammatory response syndrome were associated with use of catheter salvage. Relapse of infection was uncommon.

Keywords: Catheter salvage; Central line; Central line–associated bloodstream infection; Home infusion.

Publication types

Research Support, N.I.H., Extramural
Research Support, U.S. Gov't, P.H.S.

MeSH terms

Adult
Aged
Anti-Infective Agents, Local / therapeutic use
Bacteremia / drug therapy
Bacteremia / epidemiology*
Case-Control Studies
Catheter-Related Infections / epidemiology*
Catheterization, Central Venous / adverse effects*
Catheters, Indwelling / adverse effects
Cross Infection / epidemiology*
Female
Home Infusion Therapy / adverse effects*
Humans
Male
Middle Aged
Multivariate Analysis
Pennsylvania / epidemiology
Retrospective Studies
Risk Factors
Salvage Therapy

Substances

Anti-Infective Agents, Local

Abstract

Publication types

MeSH terms

Substances

Grants and funding