Intensive management of high-utilizing adults with sickle cell disease lowers admissions

Am J Hematol. 2015 Mar;90(3):215-9. doi: 10.1002/ajh.23912. Epub 2015 Jan 16.

Abstract

A minority of super-utilizing adults with sickle cell disease (SCD) account for a disproportionate number of emergency department (ED) and hospital admissions. We performed a retrospective cohort study comparing the rate of admission before and after the opening of a clinic for adults with SCD. Unique to this clinic was an intensive management strategy, focusing on super-utilizing adults with 12 or more admissions per year. ED/hospital and 30 days re-admission rates were compared, 1 year pre- and post-intervention, for those adults who established in the clinic. Prior to the intervention, 17 super-utilizers, comprising 15% of the pre-intervention cohort (n = 115), accounted for 58% of the total admissions and had an admission rate of 28 per patient-year. When pre- and post-intervention years were compared, rate of ED/hospital admission per patient-year for super-utilizers decreased from 27.9 to 13.5 (P < 0.001), while there was not a significant reduction for the entire cohort (7.1 vs. 6.1, P = 0.84). Similarly, the decrease in rate of 30 day re-admission was larger for the super-utilizers (13.5 per patient-year to 1.8, P < 0.001), than the whole cohort (2.6 per patient-year to 0.7, P = 0.006). Among the super-utilizers, the reduced rate of admission from the pre- to post-clinic intervention year equated to 252 fewer ED/hospital admissions and 227 fewer 30 day re-admissions. This management strategy focusing on super-utilizing adults with SCD lowered admission and 30 day re-admission rate.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Analgesics / therapeutic use
  • Anemia, Sickle Cell / therapy*
  • Antisickling Agents / therapeutic use*
  • Blood Transfusion
  • Disease Management
  • Emergency Service, Hospital / statistics & numerical data
  • Female
  • Health Services Misuse / prevention & control
  • Health Services Misuse / statistics & numerical data*
  • Hospitalization / statistics & numerical data*
  • Humans
  • Hydroxyurea / therapeutic use*
  • Male
  • Retrospective Studies

Substances

  • Analgesics
  • Antisickling Agents
  • Hydroxyurea