[Sensitisation profile to airborne allergens of patients followed for asthma in Cotonou, Benin. A cross-sectional study using prick-tests]

Rev Mal Respir. 2015 Nov;32(9):930-5. doi: 10.1016/j.rmr.2014.09.008. Epub 2014 Nov 6.
[Article in French]

Abstract

Rationale: The sensitisation profile to airborne allergens of asthma patients followed in Benin is not known.

Patients and methods: A descriptive cross-sectional study was conducted from April to June 2013 at the hospital reference centre. A prick-test was performed in all adults with asthma consulting during this period. The standardized allergenic extracts tested were: mites (Dermatophagoides pteronyssinus [DP], Dermatophagoides farinae [DF] and Blomia tropicalis [BT]), cockroaches, 5 different grasses, Alternaria, dogs and cats. The test was positive when the diameter of the wheal was more than half that of the positive control and/or when the diameter of the wheal was ≥3mm than the negative control.

Results: Of the 253 asthmatics tested, 247 (97.6%) had at least one positive skin reaction. The average age was 44 years, the sex ratio was 0.81. Sensitization to mites was the most frequent (99.6%), followed by cockroaches (71.3%), 5 grasses (71.3%), Alternaria (71%), dog (68%) and cat (63.6%). The average number of sensitivities was 5±2.

Conclusion: Asthmatics monitored in Cotonou have multiple sensitisations dominated by mites.

Keywords: Acariens; Airborne allergen; Allergie; Allergy; Asthma; Asthme; Mites; Pneumallergène; Prick-test; Skin prick-test.

Publication types

  • English Abstract

MeSH terms

  • Adult
  • Air Pollutants / immunology
  • Allergens / immunology*
  • Animals
  • Asthma / complications
  • Asthma / epidemiology*
  • Asthma / immunology*
  • Benin / epidemiology
  • Cats
  • Cross-Sectional Studies
  • Dermatophagoides farinae / immunology
  • Dermatophagoides pteronyssinus / immunology
  • Dogs
  • Female
  • Humans
  • Hypersensitivity / complications
  • Hypersensitivity / diagnosis
  • Hypersensitivity / epidemiology*
  • Male
  • Middle Aged
  • Poaceae / immunology
  • Skin Tests
  • Young Adult

Substances

  • Air Pollutants
  • Allergens