Detection of Clostridium difficile toxin genes by PCR: sequence variation may cause false-negative results

J Med Microbiol. 2015 Feb;64(Pt 2):195-197. doi: 10.1099/jmm.0.081364-0. Epub 2014 Dec 5.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Bacterial Proteins / genetics*
  • Bacterial Toxins / genetics*
  • Clostridioides difficile / genetics*
  • Clostridioides difficile / isolation & purification
  • Clostridium Infections / diagnosis
  • Clostridium Infections / microbiology
  • Enterotoxins / genetics*
  • False Negative Reactions*
  • Genetic Variation*
  • Humans
  • Polymerase Chain Reaction / methods*

Substances

  • Bacterial Proteins
  • Bacterial Toxins
  • Enterotoxins
  • tcdA protein, Clostridium difficile
  • toxB protein, Clostridium difficile