Chemical shift assignments of mouse HOXD13 DNA binding domain bound to duplex DNA

Matthew Turner; Yonghong Zhang; Hanqian L Carlson; H Scott Stadler; James B Ames

doi:10.1007/s12104-014-9589-4

Chemical shift assignments of mouse HOXD13 DNA binding domain bound to duplex DNA

Biomol NMR Assign. 2015 Oct;9(2):267-70. doi: 10.1007/s12104-014-9589-4. Epub 2014 Dec 10.

Authors

Matthew Turner¹, Yonghong Zhang¹, Hanqian L Carlson², H Scott Stadler^{2

3}, James B Ames⁴

Affiliations

¹ Department of Chemistry, University of California, Davis, CA, 95616, USA.
² Shriners Hospital for Children Research Department, 3101 SW Sam Jackson Park Road, Portland, OR, 97239, USA.
³ Department of Molecular and Medical Genetics, Oregon Health and Science University, 3181 SW Sam Jackson Park Road, Portland, OR, 97239, USA.
⁴ Department of Chemistry, University of California, Davis, CA, 95616, USA. [email protected].

Abstract

The homeobox gene (Hoxd13) codes for a transcription factor protein that binds to AT-rich DNA sequences and controls expression of proteins that control embryonic morphogenesis. We report NMR chemical shift assignments of mouse Hoxd13 DNA binding domain bound to an 11-residue DNA duplex (BMRB No. 25133).

Keywords: DNA binding domain; Duplex DNA; HOXD13; Homeodomain; NMR.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Amino Acid Sequence
Animals
DNA / metabolism*
Homeodomain Proteins / chemistry*
Homeodomain Proteins / metabolism*
Mice
Molecular Sequence Data
Nuclear Magnetic Resonance, Biomolecular*
Protein Structure, Secondary
Protein Structure, Tertiary
Proton Magnetic Resonance Spectroscopy
Transcription Factors / chemistry*
Transcription Factors / metabolism*

Substances

Homeodomain Proteins
Hoxd13 protein, mouse
Transcription Factors
DNA

Abstract

Publication types

MeSH terms

Substances

Grants and funding