Relationships between immunoglobulin and fat-soluble vitamins in colostrum of Japanese Black multiparous cows

Anim Sci J. 2015 Jul;86(7):673-8. doi: 10.1111/asj.12351. Epub 2014 Dec 11.

Abstract

Data from 19 Japanese Black multiparous cows were collected to clarify the relationships among immunoglobulin (Ig) G, IgA, β-carotene, vitamin A and α-tocopherol contents in colostrum of cows in order to evaluate the role of fat-soluble vitamins on colostral IgG and IgA production. Mean colostral IgG was 141 mg/mL, ranging from 65 to 208 mg/mL, whereas mean colostral IgA was 8.7 mg/mL, ranging from 1.0 to 34.6 mg/mL. Colostral IgG increased with aging in multiparous cows. There were positive correlations between colostral IgG and colostral vitamin A or colostral α-tocopherol in cows, and the higher adjusted R(2) was obtained in the prediction model of colostral IgG from age and colostral vitamin A. Colostral vitamin A was positively correlated with colostral β-carotene or colostral α-tocopherol in cows, but there were no relationships between colostral IgA and colostral IgG or colostral fat-soluble vitamins. These results indicate that fat-soluble vitamin contents in colostrum of cows may change in similar patterns and high colostral vitamin A is related with high colostral IgG.

Keywords: Japanese Black cow; colostral IgA; colostral IgG; vitamin A; β-carotene.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aging / metabolism
  • Animals
  • Cattle / metabolism*
  • Colostrum / chemistry*
  • Female
  • Immunoglobulin A / analysis*
  • Immunoglobulin G / analysis*
  • Japan
  • Solubility
  • Vitamin A / analysis*
  • alpha-Tocopherol / analysis*
  • beta Carotene / analysis*

Substances

  • Immunoglobulin A
  • Immunoglobulin G
  • beta Carotene
  • Vitamin A
  • alpha-Tocopherol