Distribution and accumulative pattern of tetracyclines and sulfonamides in edible vegetables of cucumber, tomato, and lettuce

J Agric Food Chem. 2015 Jan 21;63(2):398-405. doi: 10.1021/jf5034637. Epub 2015 Jan 9.

Abstract

Veterinary antibiotics can be released to environment by the animals' excretions, which thereby poses human health and ecological risks. Six antibiotics (tetracycline, oxytetracycline, chlortetracycline, sulfamethazine, sulfamethoxazole, and sulfadimethoxine) at three concentrations (5, 10, and 20 mg kg(-1) soil) were employed in pots filled with a loamy sand upland soil. Three types of vegetable seedlings, including cucumber (Cucumis sativus), cherry tomato (Solanum lycopersicum), and lettuce (Lactuca sativa), were also cultivated during 45 d in the greenhouse. All antibiotics taken up by tested plants showed negative effects on growth. Relatively high levels of tetracyclines and sulfonamides (SAs) were detected in the nonedible parts, roots, and leaves of cucumber and tomato, but fruit parts accumulated them lower than acceptable daily intake. Indeed, cucumber roots accumulated SAs by up to 94.6% of total addition (at 5 mg kg(-1) soil).

Keywords: bioaccumulation; emerging contaminant; pharmaceuticals; phytoavailability; risk assessment; veterinary antibiotics.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Anti-Bacterial Agents / analysis*
  • Anti-Bacterial Agents / metabolism
  • Cattle
  • Cucumis sativus / chemistry*
  • Cucumis sativus / growth & development
  • Cucumis sativus / metabolism
  • Feces / chemistry
  • Fruit / chemistry
  • Fruit / metabolism
  • Lactuca / chemistry*
  • Lactuca / growth & development
  • Lactuca / metabolism
  • Plant Leaves / chemistry
  • Plant Leaves / metabolism
  • Plant Roots / chemistry
  • Plant Roots / metabolism
  • Soil Pollutants / analysis
  • Soil Pollutants / metabolism
  • Solanum lycopersicum / chemistry*
  • Solanum lycopersicum / growth & development
  • Solanum lycopersicum / metabolism
  • Sulfonamides / analysis*
  • Sulfonamides / metabolism
  • Tetracyclines / analysis*
  • Tetracyclines / metabolism
  • Vegetables / chemistry*
  • Vegetables / growth & development
  • Vegetables / metabolism
  • Veterinary Drugs / analysis*
  • Veterinary Drugs / metabolism

Substances

  • Anti-Bacterial Agents
  • Soil Pollutants
  • Sulfonamides
  • Tetracyclines
  • Veterinary Drugs