Abstract
We report a case of meningoencephalitis caused by Toscana virus (TOSV) with central facial paralysis lasting over two days acquired in south-eastern France. The patient was not febrile either before or during the course of the disease. The diagnosis was established by both real-time RT-PCR and virus isolation with complete genome sequencing. This case emphasises the need to consider TOSV in non-febrile neurological syndromes in people living in or having travelled to the Mediterranean area.
Publication types
-
Case Reports
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Acyclovir / therapeutic use
-
Adult
-
Amoxicillin / therapeutic use
-
Animals
-
Anti-Bacterial Agents / therapeutic use
-
Antiviral Agents / therapeutic use
-
Bunyaviridae Infections / diagnosis*
-
Bunyaviridae Infections / drug therapy
-
Ceftriaxone / therapeutic use
-
Facial Paralysis / etiology*
-
Female
-
France
-
Genome, Viral / genetics
-
Humans
-
Insect Vectors / virology
-
Meningoencephalitis / diagnosis*
-
Meningoencephalitis / virology
-
RNA, Viral / genetics
-
RNA, Viral / isolation & purification
-
Reverse Transcriptase Polymerase Chain Reaction
-
Sandfly fever Naples virus / genetics
-
Sandfly fever Naples virus / isolation & purification*
-
Sequence Analysis, RNA
-
Treatment Outcome
Substances
-
Anti-Bacterial Agents
-
Antiviral Agents
-
RNA, Viral
-
Ceftriaxone
-
Amoxicillin
-
Acyclovir