Can α-lipoic acid mitigate progression of aging-related decline caused by oxidative stress?

South Med J. 2014 Dec;107(12):780-7. doi: 10.14423/SMJ.0000000000000198.

Abstract

Aging is progressively deteriorating physiological function that leads to increasing risks of illness and death. Increases in life expectancy and the aging of a large segment of the population have made age-related disability and morbidity increasingly important issues. Supplements such as α-lipoic acid may have antiaging effects by positively affecting oxidative stress, cognitive function, and cardiovascular function.

Publication types

  • Review

MeSH terms

  • Aging / drug effects*
  • Aging / physiology
  • Antioxidants / pharmacology*
  • Dietary Supplements*
  • Humans
  • Oxidative Stress / drug effects*
  • Thioctic Acid / pharmacology*

Substances

  • Antioxidants
  • Thioctic Acid