A versatile 'click chemistry' route to size-restricted, robust, and functionalizable hydrophilic nanocrystals

Tong Bian; Chao Wang; Zhenda Lu; Renguo Xie; Qing-Zheng Yang; Li-Zhu Wu; Chen-Ho Tung; Zhuang Liu; Yadong Yin; Tierui Zhang

doi:10.1002/smll.201400673

A versatile 'click chemistry' route to size-restricted, robust, and functionalizable hydrophilic nanocrystals

Small. 2015 Apr 8;11(14):1644-8. doi: 10.1002/smll.201400673. Epub 2014 Dec 15.

Authors

Tong Bian¹, Chao Wang, Zhenda Lu, Renguo Xie, Qing-Zheng Yang, Li-Zhu Wu, Chen-Ho Tung, Zhuang Liu, Yadong Yin, Tierui Zhang

Affiliation

¹ Key Laboratory of Photochemical Conversion and Optoelectronic Materials, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing, 100190, P. R. China.

PMID: 25504669
DOI: 10.1002/smll.201400673

Abstract

A versatile addition-crosslinking route is developed to transfer various hydrophobic nanocrystals into water. By assembling amphiphilic ligands and then crosslinking through 'click chemistry', a monolayer of polymer forms on the nanocrystal surface, leading to excellent stability and limited increase in hydrodynamic diameter. These nanocrystals can also be further functionalized easily for various applications such as catalysis, bioimaging, and medical therapy.

Keywords: Click Chemistry; functionalization; hydrophilic nanocrystals; nanocrystals; phase transfer; storage stability.

Publication types

Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

Click Chemistry*
Hydrophobic and Hydrophilic Interactions*
Microscopy, Electron, Transmission
Nanoparticles*
Spectrophotometry, Ultraviolet
Spectroscopy, Fourier Transform Infrared