Emergence of a KPC-3-Producing Escherichia coli ST69 as a Cause of Bloodstream Infections in Italy

Daniele Roberto Giacobbe; Valerio Del Bono; Erika Coppo; Anna Marchese; Claudio Viscoli

doi:10.1089/mdr.2014.0230

Emergence of a KPC-3-Producing Escherichia coli ST69 as a Cause of Bloodstream Infections in Italy

Microb Drug Resist. 2015 Jun;21(3):342-4. doi: 10.1089/mdr.2014.0230. Epub 2014 Dec 16.

Authors

Daniele Roberto Giacobbe¹, Valerio Del Bono¹, Erika Coppo², Anna Marchese², Claudio Viscoli¹

Affiliations

¹ 1Infectious Diseases Unit, IRCCS San Martino University Hospital-IST, University of Genoa, Genoa, Italy.
² 2Microbiology Unit DISC, IRCCS San Martino University Hospital-IST, University of Genoa, Genoa, Italy.

PMID: 25514440
DOI: 10.1089/mdr.2014.0230

Abstract

The spread of carbapenem-resistant gram negatives is a global emergency, and surveillance of new resistant clones is critical from both public health and clinical standpoints. Herein, we describe the emergence of a KPC-3-producing Escherichia coli ST69 as a cause of bloodstream infection in two Italian patients.

Publication types

Case Reports

MeSH terms

Aged
Aged, 80 and over
Anti-Bacterial Agents / therapeutic use*
Bacteremia / drug therapy*
Bacteremia / microbiology
Ciprofloxacin / therapeutic use
Escherichia coli / drug effects*
Escherichia coli / enzymology
Escherichia coli / genetics
Escherichia coli Infections / drug therapy*
Escherichia coli Infections / microbiology
Gene Expression
Gentamicins / therapeutic use
Humans
Italy
Male
Microbial Sensitivity Tests
Minocycline / analogs & derivatives
Minocycline / therapeutic use
Tigecycline
Treatment Outcome
beta-Lactam Resistance / genetics*
beta-Lactamases / genetics*
beta-Lactamases / metabolism

Substances

Anti-Bacterial Agents
Gentamicins
Ciprofloxacin
Tigecycline
beta-Lactamases
Minocycline