Existing records of 96 patients with small cell lung cancer (SCLC) at TSGH from 1983 to 1987 were analyzed to determine the relationship of survival rate and prognostic factors including age, sex stage, symptomatic history, liver metastasis, bone metastasis, albumin level, hemoglobin value, and choice of treatment. For the SCLC patients the median survival time (MST) is only 7.2 month, the 1-year survival rate is 25.1%, and the 2-year survival rate is 5.1%. The prognosis for patients with liver or bone metastasis was poor. Sixteen prognostic variables were evaluated in a Cox proportional hazard regression model analysis to assess their prognostic value. It is suggested that improving survival rate for patients with SCLS can be obtained by using selective combined therapy.