Mycobacterium avium complex-associated peritonitis with CAPD after unrelated bone marrow transplantation

Pediatr Int. 2014 Dec;56(6):e96-e98. doi: 10.1111/ped.12463.

Abstract

Peritonitis remains an important complication of peritoneal dialysis and is mostly caused by aerobic enteric bacteria. Non-tuberculous mycobacteria (NTM)-associated peritonitis is an unusual but serious infection, requiring special culture techniques to avoid delay in diagnosis. We report the case of an 11-year-old girl with aplastic anemia on ambulatory peritoneal dialysis who had Mycobacterium avium complex-associated peritonitis after allogeneic hematopoietic stem cell transplantation (allo-HSCT). This case emphasizes that we should be constantly cautious about NTM infection in allo-HSCT recipients, especially when standard cultures are negative and the infection is refractory to empirical antibiotic therapy.

Keywords: B-cell; immunosuppression; non-tuberculous mycobacteria.

Publication types

  • Case Reports

MeSH terms

  • Anemia, Aplastic / complications
  • Anemia, Aplastic / therapy*
  • Bone Marrow Transplantation / adverse effects*
  • Child
  • Female
  • Humans
  • Mycobacterium avium Complex*
  • Peritoneal Dialysis, Continuous Ambulatory*
  • Peritonitis / etiology*
  • Renal Insufficiency / complications
  • Renal Insufficiency / therapy*