Combined microwave thermal ablation and liver resection for single step treatment of otherwise unresectable colorectal liver metastases; a monoistitutional experiences

Eur Rev Med Pharmacol Sci. 2014 Dec;18(2 Suppl):6-10.

Abstract

Objective: Over half of colorectal cancer patients will develop liver metastases.

Background: Thermal ablation with or without associated liver resection for colorectal hepatic metastasis has been suggested as an alternative method to improve survival if radical surgical resection is not achievable. A retrospective case series of patients treated with microwave ablation(MWA) associated with hepatic resection in one step procedure, was reviewed to analyze the clinical outcome.

Materials and methods: In a group of 40 patients surgically cured for liver tumors in our Department, 5 patients with technically unresectable disease underwent combined treatment LR-MWA.

Results: Four patients were treated with multiple segmentectomies and MWA and one patient received a left lobectomy (S2-S3) and MWA. Only 1 patient (20%) developed post surgical complication which was a liver abscess (grade II of Dindo classification).

Conclusions: Hepatic resection combined with MWA expanded indications for operative treatment of multiple bilobar liver metastasis. This procedure promise to have good long-term outcomes.

MeSH terms

  • Adult
  • Aged
  • Catheter Ablation / methods*
  • Colorectal Neoplasms / pathology*
  • Colorectal Neoplasms / surgery*
  • Combined Modality Therapy
  • Female
  • Hepatectomy / methods
  • Humans
  • Liver Neoplasms / secondary*
  • Liver Neoplasms / surgery*
  • Male
  • Microwaves / therapeutic use*
  • Middle Aged
  • Retrospective Studies