Two-exponential analysis of spin-spin proton relaxation times in MR imaging using surface coils

Magn Reson Imaging. 1989 Jul-Aug;7(4):357-62. doi: 10.1016/0730-725x(89)90484-0.

Abstract

Proton relaxation time measurements were performed on a standard whole body MR imager operating at 1.5 T using a conventional surface coil of the manufacturer. A combined CP/CPMG multiecho, multislice sequence was used for the T1 and T2 relaxation time measurements. Two repetition times of 2000 ms (30 echoes) and 600 ms (2 echoes) with 180 degrees-pulse intervals of 2 tau = 22 ms were interleaved in this sequence. A two-exponential T2 analysis of each pixel of the spin-echo images was computed in a case of an acoustic neurinoma. The two-exponential images show a "short" component (T2S) due to white and gray matter and a "long" component (T2S) due to the cerebrospinal fluid. In the fatty tissue two components with T2S = 35 +/- 3 ms and T2L = 164 +/- 7 ms were measured. Comparing with Gd-DTPA imaging the relaxation time images show a clear differentiation of vital tumor tissue and cerebrospinal fluid.

MeSH terms

  • Equipment Design
  • Evaluation Studies as Topic
  • Humans
  • Magnetic Resonance Imaging / instrumentation*
  • Magnetic Resonance Imaging / methods
  • Protons
  • Time Factors

Substances

  • Protons