[Antiphosphatidylethanolamine antibody as a marker of antiphospholipid syndrome?]

Presse Med. 2015 Mar;44(3):284-91. doi: 10.1016/j.lpm.2014.06.033. Epub 2014 Dec 24.
[Article in French]

Abstract

Antibody to phosphatidylethanolamine (aPE) are observed in thrombotic or obstetric manifestations suggestive of antiphospholipid syndrome (APS). aPE seem to be markers of thrombotic risk independent of conventional antiphospholipid antibodies (aPL). aPE assays are not standardized. There is no therapeutic recommendation for isolated aPE patients with thrombotic or obstetric events. Prospective studies have to be carried to better define the therapeutic management of these patients. Value of aPE in APS criteria is still not established.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Antibodies, Antiphospholipid / analysis
  • Antibodies, Antiphospholipid / blood*
  • Antiphospholipid Syndrome / blood
  • Antiphospholipid Syndrome / diagnosis*
  • Antiphospholipid Syndrome / epidemiology
  • Biomarkers / analysis
  • Biomarkers / blood*
  • Female
  • Humans
  • Phosphatidylethanolamines / immunology*
  • Pregnancy
  • Pregnancy Complications / diagnosis
  • Pregnancy Complications / epidemiology
  • Pregnancy Complications / immunology
  • Thrombosis / blood
  • Thrombosis / diagnosis
  • Thrombosis / immunology

Substances

  • Antibodies, Antiphospholipid
  • Biomarkers
  • Phosphatidylethanolamines
  • phosphatidylethanolamine