Selective loss of vaccine-specific memory B cells in a rhesus macaque model of chemotherapy: influence of doxorubicin on immunological memory

Haematologica. 2015 Apr;100(4):e158-61. doi: 10.3324/haematol.2014.116111. Epub 2014 Dec 31.
No abstract available

Keywords: B cells; BMPC; T cells; chemotherapy; doxorubicin; response to vaccines.

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Antineoplastic Agents / pharmacology
  • Antineoplastic Agents / therapeutic use*
  • B-Lymphocytes / drug effects
  • B-Lymphocytes / immunology*
  • B-Lymphocytes / metabolism
  • Cancer Vaccines / immunology*
  • Disease Models, Animal
  • Doxorubicin / pharmacology
  • Doxorubicin / therapeutic use*
  • Immunologic Memory* / drug effects
  • Macaca mulatta
  • Neoplasms / immunology*
  • Neoplasms / therapy*
  • T-Lymphocytes / drug effects
  • T-Lymphocytes / immunology
  • T-Lymphocytes / metabolism

Substances

  • Antineoplastic Agents
  • Cancer Vaccines
  • Doxorubicin