ST2: the biomarker at the heart of GVHD severity

Blood. 2015 Jan 1;125(1):10-1. doi: 10.1182/blood-2014-11-611780.

Abstract

In this issue of Blood, Ponce et al report that high suppression of tumorigenicity 2 (ST2) levels are significantly associated with the incidence of acute graft-versus-host disease (aGVHD) and transplant-related mortality (TRM) in recipients of double-unit cord blood transplants (CBTs).

Publication types

  • Comment

MeSH terms

  • Biomarkers / blood*
  • Cord Blood Stem Cell Transplantation / adverse effects*
  • Female
  • Graft vs Host Disease / diagnosis*
  • Hematologic Neoplasms / mortality*
  • Hematologic Neoplasms / therapy*
  • Humans
  • Interleukin-1 Receptor-Like 1 Protein
  • Male
  • Receptors, Cell Surface / blood*

Substances

  • Biomarkers
  • IL1RL1 protein, human
  • Interleukin-1 Receptor-Like 1 Protein
  • Receptors, Cell Surface