[SPECT, coronary angio-CT, invasive coronary angiography and fusion images in stable coronary disease]

Rev Esp Med Nucl Imagen Mol. 2015 May-Jun;34(3):173-80. doi: 10.1016/j.remn.2014.11.004. Epub 2014 Dec 30.
[Article in Spanish]

Abstract

Objectives: To evaluate the usefulness of the information obtained with SPECT, coronary angio-CT and fusion images, in patients with stable ischemic disease who need invasive coronary angiography (IA).

Material and methods: Forty-six patients (65.98±8.3 years) with coronary disease were prospectively included. The fusion images generated after undergoing IA were used to evaluate the performance of these techniques in the diagnosis of multi-vessel coronary disease, the detection of the culprit vessel and the therapeutic management of these patients.

Results: In the IA, 29 of the 46 patients (63%) had multi-vessel disease. SPECT could detect it in 48.2% and coronary angio-CT could detect it in 89.6%. Concordance between coronary angio-CT and IA in the diagnosis of the culprit vessel was 77% (kappa 0.6), and between SPECT and IA it was 73% (kappa 0.56). Although fusion images could have been obtained prior to IA, they would not have changed the therapeutic approach derived from SPECT and IA.

Conclusions: Coronary angio-CT has a high ability for the diagnosis of multi-vessel disease and the culprit lesion, and SPECT is a good functional complement of the IA in the detection of the most ischemic territory. However, the performance of fusion images in patients with stable ischemic disease, who have undergone a SPECT as the first non-invasive study and need IA, does not seem indicated because they would not have changed the therapeutic management derived from SPECT and IA information.

Keywords: Angio-TC; Cardiopatía isquémica estable; Coronary angio-CT; Culprit vessel; Enfermedad multivaso; Fusión SPECT-TC; Gated-SPECT; Multi-vessel disease; SPECT-CT image fusion; Stable ischemic disease; Vaso culpable.

MeSH terms

  • Aged
  • Cardiac-Gated Single-Photon Emission Computer-Assisted Tomography / methods
  • Coronary Angiography / methods*
  • Coronary Artery Disease / diagnostic imaging*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Myocardial Perfusion Imaging / methods*
  • Myocardial Revascularization
  • Prospective Studies
  • Single Photon Emission Computed Tomography Computed Tomography
  • Single-Blind Method
  • Tomography, Emission-Computed, Single-Photon / methods*
  • Tomography, X-Ray Computed / methods*