A near-infrared light-controlled system for reversible presentation of bioactive ligands using polypeptide-engineered functionalized gold nanorods

Chem Commun (Camb). 2015 Feb 14;51(13):2569-72. doi: 10.1039/c4cc09516b.

Abstract

A near-infrared light-controlled hybrid platform with polypeptide-engineered functionalized gold nanorods has been designed for reversible presentation of the immobilized ligands to cell surface receptors on the engineered materials.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Cell Survival / drug effects
  • Dose-Response Relationship, Drug
  • Gold / chemistry*
  • Gold / pharmacology
  • Infrared Rays*
  • Ligands
  • Mice
  • NIH 3T3 Cells
  • Nanotubes / chemistry*
  • Peptides / chemistry*
  • Peptides / pharmacology
  • Protein Engineering*
  • Structure-Activity Relationship

Substances

  • Ligands
  • Peptides
  • Gold