Safety assessment of Tin(IV) oxide as used in cosmetics

Int J Toxicol. 2014 Nov-Dec;33(4 Suppl):40S-6S. doi: 10.1177/1091581814559309.

Abstract

Tin(IV) oxide functions as an abrasive, bulking, and opacifying agent in cosmetic products and is used at concentrations up to 0.4% in rinse-off products and up to 1.3% in leave-on products. The Cosmetic Ingredient Review Expert Panel (Panel) noted that tin(IV) oxide is a water-insoluble inorganic metal compound and should not be percutaneously absorbed; therefore, systemic exposure is not likely. Studies of dermal application of tin(IV) oxide were considered to determine toxicity at the site of application. The Panel concluded that tin(IV) oxide is safe in the present practices of use and concentration.

Keywords: cosmetics; safety; tin oxide.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Consumer Product Safety
  • Cosmetics / toxicity*
  • Dermatitis, Irritant / etiology*
  • Eye Diseases / chemically induced*
  • Female
  • Humans
  • Lung Diseases / chemically induced*
  • Male
  • Middle Aged
  • Occupational Diseases / chemically induced*
  • Peritoneal Diseases / chemically induced*
  • Risk Assessment
  • Tin Compounds / toxicity*
  • Toxicity Tests
  • United States
  • Young Adult

Substances

  • Cosmetics
  • Tin Compounds
  • stannic oxide