[Painful legs and moving toes. Neuropathy caused by cytarabine]

Rev Neurol (Paris). 1989;145(12):869-71.
[Article in French]

Abstract

A new case of painful legs and moving toes syndrome is reported in a patient with a neuropathy due to high-doses of cytosine arabinoside (Ara C). A few cases of this complication have been reported. The neuropathy was sensory, axonal, and incompletely regressive. Carbamazepine had a dramatic effect on pain and involuntary movements.

Publication types

  • Case Reports
  • English Abstract
  • Review

MeSH terms

  • Adolescent
  • Axons
  • Carbamazepine / therapeutic use
  • Cytarabine / administration & dosage
  • Cytarabine / adverse effects*
  • Dose-Response Relationship, Drug
  • Humans
  • Leg / innervation*
  • Male
  • Movement Disorders / drug therapy
  • Movement Disorders / etiology*
  • Pain / drug therapy
  • Pain / etiology
  • Peripheral Nervous System Diseases / chemically induced*
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / drug therapy*
  • Reflex, Abnormal
  • Sensory Receptor Cells
  • Syndrome
  • Toes / injuries*
  • Toes / physiopathology

Substances

  • Cytarabine
  • Carbamazepine