Sacral anterior root stimulation improves bowel function in subjects with spinal cord injury

Spinal Cord. 2015 Apr;53(4):297-301. doi: 10.1038/sc.2015.2. Epub 2015 Jan 20.

Abstract

Study design: Cross-sectional study.

Objective: To evaluate the long-term effect of the sacral anterior root stimulator (SARS) on neurogenic bowel dysfunction in a large, well defined spinal cord injury (SCI) cohort.

Setting: Department of Neuro-Urology, Bad Wildungen, Germany.

Methods: Subjects undergone surgery at for SARS-SDAF (sacral deafferentation) between September 1986 and July 2011 (n=587) answered a questionnaire. In total, 277 SARS subjects were available for the baseline (recall) and follow-up comparison.

Results: Median age was 49 years (range: 19-80), time from SCI to surgery was 10 years (range: 0-49) and from surgery to follow-up 13 (range: 1-25). Of the responders 73% used SARS for bowel emptying. On visual analog scale (VAS) ranging from 0-10 (best), satisfaction with SARS was 10. Baseline and follow-up comparison showed a decline in the median VAS score 0-10 (worst) for bowel symptoms from 6 (range: 4-8) to 4 (range: 2-6), P<0.0001; median neurogenic bowel dysfunction score from 17 (range: 11-2) to 11 (range: 9-15), P<0.0001; median St Marks score from 4 (range: 0-7) to 4 (range: 0-5), P=0.01; and median Cleveland constipation score from 7 (range: 6-10) to 6 (range: 4-8), P<0.0001. Use of suppositories, digital evacuation and mini enema and subjects totally dependent on assistance during defecation were significantly lower after SARS.

Conclusions: The SARS has the potential to be one of the few treatment methods targeting multiple organ dysfunctions following SCI.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Constipation / physiopathology
  • Constipation / therapy*
  • Cross-Sectional Studies
  • Electric Stimulation Therapy / methods*
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Middle Aged
  • Neurogenic Bowel / physiopathology
  • Neurogenic Bowel / therapy*
  • Sacrum
  • Spinal Cord Injuries / physiopathology
  • Spinal Cord Injuries / therapy*
  • Spinal Nerve Roots / physiopathology
  • Spinal Nerve Roots / surgery*
  • Surveys and Questionnaires
  • Treatment Outcome
  • Young Adult