Influence of spinal cord lesion level and severity on H-reflex excitability and recovery curve

Muscle Nerve. 2015 Oct;52(4):616-22. doi: 10.1002/mus.24579. Epub 2015 Jun 30.

Abstract

Introduction: Changes in spinal reflexes can result from alterations in the spinal cord and descending pathways. We studied whether H-reflex excitability and its recovery depend on the level and/or severity of spinal cord injury (SCI).

Methods: The soleus Hmax and Mmax responses and the H-reflex recovery curve (HRC) at interstimulus intervals (ISIs) ranging from 50 to 1,000 ms were recorded in 38 SCI individuals and 18 healthy subjects.

Results: Amplitude of Mmax correlated with level and severity of lesion (smaller amplitude correlated with more severe SCI or with more caudal lesion). Hmax/Mmax correlated only with age in the SCI group. HRC was increased significantly in complete SCI at ISIs < 500 ms and in incomplete SCI at ISIs > 200 ms with respect to healthy subjects.

Conclusions: The changes in spinal reflexes as measured by the H-reflex and its recovery curve after SCI depend on the severity, but not on the level of the lesion.

Keywords: H-reflex; severity of SCI; spinal cord injury; spinal level.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Analysis of Variance
  • Biophysics
  • Electric Stimulation
  • Electromyography
  • Female
  • H-Reflex / physiology*
  • Humans
  • Male
  • Middle Aged
  • Muscle, Skeletal / physiopathology*
  • Spinal Cord Injuries / pathology*
  • Spinal Cord Injuries / physiopathology*
  • Time Factors
  • Young Adult