Clinical evaluation of the OneStep Gonorrhea RapiCard InstaTest for detection of Neisseria gonorrhoeae in symptomatic patients from KwaZulu-Natal, South Africa

N S Abbai; P Moodley; T Reddy; T G Zondi; S Rambaran; K Naidoo; G Ramjee

doi:10.1128/JCM.03603-14

Clinical evaluation of the OneStep Gonorrhea RapiCard InstaTest for detection of Neisseria gonorrhoeae in symptomatic patients from KwaZulu-Natal, South Africa

J Clin Microbiol. 2015 Apr;53(4):1348-50. doi: 10.1128/JCM.03603-14. Epub 2015 Jan 21.

Authors

N S Abbai¹, P Moodley², T Reddy³, T G Zondi⁴, S Rambaran⁵, K Naidoo⁵, G Ramjee⁶

Affiliations

¹ HIV Prevention Research Unit, Medical Research Council, Westville, Durban, South Africa [email protected].
² Infectious Diseases, School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, Durban, South Africa Infection Prevention and Control, KwaZulu-Natal Department of Health, Durban, South Africa.
³ Biostatistics Unit, Medical Research Council, Durban, South Africa.
⁴ HIV Prevention Research Unit, Medical Research Council, Westville, Durban, South Africa.
⁵ Infectious Diseases, School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, Durban, South Africa.
⁶ HIV Prevention Research Unit, Medical Research Council, Westville, Durban, South Africa Department of Epidemiology and Population Health, London School of Hygiene & Tropical Medicine, London, United Kingdom.

Abstract

We evaluated a point-of-care test for the detection of Neisseria gonorrhoeae in patients attending a public health clinic in KwaZulu-Natal, South Africa. The test showed a low sensitivity against PCR and culture (<40%); however, a higher specificity was observed (>95%). This test is unsuitable as a screening tool for gonorrhea.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Antigens, Bacterial / isolation & purification
Bacteriological Techniques
Female
Gonorrhea / diagnosis*
Gonorrhea / epidemiology
Gonorrhea / microbiology
Humans
Male
Neisseria gonorrhoeae / isolation & purification*
Point-of-Care Systems*
Reagent Kits, Diagnostic*
South Africa / epidemiology

Substances

Antigens, Bacterial
Reagent Kits, Diagnostic