Out of 472 patients with gestational trophoblastic disease directed to the Institute of Oncology in Warsaw in the period 1.4.1977-1.4.1987, 145 (30.7%) have been qualified for treatment. Lasting cure was obtained in all of 105 patients with the disease restricted to the uterus, in 13 of 14 (92.8%) with metastatic disease with favourable prognosis and in 20 out of 25 (80.0%) with metastatic disease with poor prognosis. In 102 patients treated exclusively chemically the procreative ability has been preserved, 33 of these women gave birth to a total of 44 healthy children.