Long-term response in a patient with ITP following low dose anti-D immunoglobulin therapy

Autoimmunity. 1989;4(1-2):115-7. doi: 10.3109/08916938909034366.

Abstract

A patient with chronic ITP relapsed after conventional therapy but following an infusion with low dose anti D (Rho) immunoglobulin, she entered a remission which has now lasted 10 months. This is difficult to explain on the basis of long term macrophage Fc receptor blockade and suggests an alternative mechanism of action.

Publication types

  • Case Reports

MeSH terms

  • Blood Platelets / immunology
  • Child
  • Female
  • Humans
  • Immunoglobulins / administration & dosage*
  • Macrophages / immunology
  • Purpura, Thrombocytopenic / blood
  • Purpura, Thrombocytopenic / immunology
  • Purpura, Thrombocytopenic / therapy*
  • Receptors, Fc
  • Rh-Hr Blood-Group System
  • Rho(D) Immune Globulin

Substances

  • Immunoglobulins
  • Receptors, Fc
  • Rh-Hr Blood-Group System
  • Rho(D) Immune Globulin