Piscine reovirus, but not Jaundice Syndrome, was transmissible to Chinook Salmon, Oncorhynchus tshawytscha (Walbaum), Sockeye Salmon, Oncorhynchus nerka (Walbaum), and Atlantic Salmon, Salmo salar L

J Fish Dis. 2016 Feb;39(2):117-28. doi: 10.1111/jfd.12329. Epub 2015 Jan 29.

Abstract

A Jaundice Syndrome occurs sporadically among sea-pen-farmed Chinook Salmon in British Columbia, the westernmost province of Canada. Affected salmon are easily identified by a distinctive yellow discolouration of the abdominal and periorbital regions. Through traditional diagnostics, no bacterial or viral agents were cultured from tissues of jaundiced Chinook Salmon; however, piscine reovirus (PRV) was identified via RT-rPCR in all 10 affected fish sampled. By histopathology, Jaundice Syndrome is an acute to peracute systemic disease, and the time from first clinical signs to death is likely <48 h; renal tubular epithelial cell necrosis is the most consistent lesion. In an infectivity trial, Chinook Salmon, Sockeye Salmon and Atlantic Salmon, intraperitoneally inoculated with a PRV-positive organ homogenate from jaundiced Chinook Salmon, developed no gross or microscopic evidence of jaundice despite persistence of PRV for the 5-month holding period. The results from this study demonstrate that the Jaundice Syndrome was not transmissible by injection of material from infected fish and that PRV was not the sole aetiological factor for the condition. Additionally, these findings showed the Pacific coast strain of PRV, while transmissible, was of low pathogenicity for Atlantic Salmon, Chinook Salmon and Sockeye Salmon.

Keywords: Atlantic Salmon; Chinook Salmon; Jaundice Syndrome; Sockeye Salmon; piscine reovirus.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acute Disease
  • Animals
  • British Columbia
  • Fish Diseases / mortality
  • Fish Diseases / pathology
  • Fish Diseases / transmission*
  • Fish Diseases / virology
  • Gene Expression Profiling
  • Gene Expression Regulation
  • Liver / physiopathology
  • Myxovirus Resistance Proteins / genetics
  • Reoviridae / pathogenicity
  • Reoviridae / physiology*
  • Reoviridae Infections / transmission
  • Reoviridae Infections / veterinary*
  • Salmonidae / genetics
  • Salmonidae / virology*
  • Syndrome

Substances

  • Myxovirus Resistance Proteins

Associated data

  • GENBANK/KC795600.1