Photothermal theragnosis synergistic therapy based on bimetal sulphide nanocrystals rather than nanocomposites

Bo Li; Kaichuang Ye; Yuxin Zhang; Jinbao Qin; Rujia Zou; Kaibing Xu; Xiaojuan Huang; Zhiyin Xiao; Wenjun Zhang; Xinwu Lu; Junqing Hu

doi:10.1002/adma.201404257

Photothermal theragnosis synergistic therapy based on bimetal sulphide nanocrystals rather than nanocomposites

Adv Mater. 2015 Feb 25;27(8):1339-45. doi: 10.1002/adma.201404257. Epub 2015 Jan 12.

Authors

Bo Li¹, Kaichuang Ye, Yuxin Zhang, Jinbao Qin, Rujia Zou, Kaibing Xu, Xiaojuan Huang, Zhiyin Xiao, Wenjun Zhang, Xinwu Lu, Junqing Hu

Affiliation

¹ State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Materials Science and Engineering, Donghua University, Shanghai, 201620, PR China.

PMID: 25639509
DOI: 10.1002/adma.201404257

Abstract

A new generation of photothermal theranostic agents is developed based on Cu3BiS3 nanocrystals. A computed tomography imaging response and photothermal effect, as well as near-infrared fluorescence emission, can be simultaneously achieved through Cu3BiS3 nanocrystals rather than frequently used nanocomposites. These results provide some insight into the synergistic effect from bimetal sulphide semiconductor compounds for photothermal theragnosis therapy.

Keywords: Cu3BiS3 nanocrystals; computed tomography (CT) imaging; near-infrared response; photothermal theragnosis therapy.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Bismuth / chemistry*
Cell Line, Tumor
Copper / chemistry*
Mice
Nanoparticles / chemistry*
Nanoparticles / therapeutic use*
Phototherapy / methods*
Sarcoma, Ewing / diagnosis
Sarcoma, Ewing / pathology
Sarcoma, Ewing / therapy
Sulfides / chemistry*
Theranostic Nanomedicine / methods*
Tomography, X-Ray Computed

Substances

Sulfides
Copper
Bismuth