Materials and fractal designs for 3D multifunctional integumentary membranes with capabilities in cardiac electrotherapy

Adv Mater. 2015 Mar 11;27(10):1731-7. doi: 10.1002/adma.201405017. Epub 2015 Jan 12.

Abstract

Advanced materials and fractal design concepts form the basis of a 3D conformal electronic platform with unique capabilities in cardiac electrotherapies. Fractal geometries, advanced electrode materials, and thin, elastomeric membranes yield a class of device capable of integration with the entire 3D surface of the heart, with unique operational capabilities in low power defibrillation. Co-integrated collections of sensors allow simultaneous monitoring of physiological responses. Animal experiments on Langendorff-perfused rabbit hearts demonstrate the key features of these systems.

Keywords: bio-electronic materials; cardiac electrotherapy; electrochemical methods; fractal designs; stretchable electronics.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Alloys / chemistry
  • Animals
  • Elastomers
  • Electric Impedance
  • Electric Stimulation Therapy / instrumentation*
  • Electric Stimulation Therapy / methods
  • Electrodes*
  • Equipment Design
  • Fractals
  • Heart* / physiology
  • Heart* / physiopathology
  • Iridium / chemistry
  • Materials Testing
  • Microscopy, Electron, Scanning
  • Nanostructures / chemistry
  • Optical Imaging
  • Platinum Compounds / chemistry
  • Polystyrenes / chemistry
  • Rabbits
  • Silicone Elastomers
  • Silver Compounds / chemistry
  • Spectrum Analysis
  • Thiophenes / chemistry
  • Titanium / chemistry

Substances

  • Alloys
  • Elastomers
  • Platinum Compounds
  • Polystyrenes
  • Silicone Elastomers
  • Silver Compounds
  • Thiophenes
  • poly(3,4-ethylenedioxythiophene)-poly(styrenesulfonate)
  • Iridium
  • Titanium