Adaptation on a genomic scale

Elife. 2015 Feb 3:4:e06193. doi: 10.7554/eLife.06193.

Authors

István Bartha¹, Jacques Fellay²

Affiliations

¹ School of Life Sciences, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland and Host-pathogen genomics group, Swiss Institute of Bioinformatics, Lausanne, Switzerland.
² School of Life Sciences, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland and Host-pathogen genomics group, Swiss Institute of Bioinformatics, Lausanne, Switzerland, [email protected].

Abstract

Sequencing the genome of Candida albicans as it evolves in a patient reveals the genetic changes that allow the yeast to adapt to its environment.

Keywords: Candida albicans; drug resistance; evolutionary biology; genomics; infectious disease; microbial evolution; microbiology; virulence.

Publication types

Comment

MeSH terms

Candida albicans / drug effects*
Candida albicans / genetics*
Candidiasis / microbiology*
Drug Resistance, Fungal / drug effects*
Drug Resistance, Fungal / genetics*
Evolution, Molecular*
Humans