Pathways from maternal depressive symptoms to adolescent depressive symptoms: the unique contribution of irritability symptoms

J Child Psychol Psychiatry. 2015 Oct;56(10):1092-100. doi: 10.1111/jcpp.12395. Epub 2015 Feb 9.

Abstract

Background: The authors tested three possible pathways linking prenatal maternal depressive symptoms to adolescent depressive symptoms. These pathways went through childhood Irritability Symptoms, Anxiety/Depressive Symptoms or Conduct Problems.

Method: Data were collected from 3,963 mother-child pairs participating in the Avon Longitudinal Study of Parents and Children. Measures include maternal depressive symptoms (pre- and postnatal); toddler temperament (2 years); childhood (7-13 years) irritability symptoms, anxiety/depressive symptoms, conduct problems, and adolescent depressive symptoms (16 years).

Results: Irritability Symptoms: This pathway linked sequentially - prenatal maternal depressive symptoms, toddler temperament (high perceived intensity and low perceived adaptability), childhood irritability symptoms, and adolescent depressive symptoms. Anxiety/Depressive symptoms: This pathway linked sequentially - prenatal maternal depressive symptoms, toddler temperament (negative perceived mood), childhood anxiety/depressive symptoms, and adolescent depressive symptoms. Childhood conduct problems were not associated with adolescent depressive symptoms, above and beyond irritability symptoms and anxiety/depressive symptoms.

Conclusions: Results suggest evidence for two distinct developmental pathways to adolescent depressive symptoms that involve specific early and midchildhood features.

Keywords: Psychopathology; depression; development; mother-child relationships; oppositional defiant disorder.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, N.I.H., Intramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adolescent Development / physiology*
  • Adult
  • Anxiety / etiology
  • Child
  • Child Development / physiology*
  • Child of Impaired Parents / psychology*
  • Child, Preschool
  • Depression* / complications
  • Depression* / etiology
  • Depression* / psychology
  • Female
  • Humans
  • Irritable Mood / physiology*
  • Male
  • Mothers / psychology*
  • Pregnancy
  • Prenatal Exposure Delayed Effects / psychology*
  • Temperament / physiology*