Protein tyrosine phosphatase 1B (PTP1B) is involved in the defective erythropoietic function of carbamylated erythropoietin

Int J Biochem Cell Biol. 2015 Apr:61:63-71. doi: 10.1016/j.biocel.2015.01.019. Epub 2015 Feb 7.
No abstract available

Keywords: Carbamylated erythropoietin; Cell proliferation; Erythropoietin; PTP1B; Tyrosine phosphatases.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cell Line
  • Cell Line, Tumor
  • Cell Proliferation / physiology
  • Cytokine Receptor Common beta Subunit / metabolism
  • Enzyme Activation
  • Erythropoietin / analogs & derivatives*
  • Erythropoietin / genetics
  • Erythropoietin / metabolism
  • Erythropoietin / pharmacology
  • Humans
  • Janus Kinase 2 / metabolism
  • Neurons / drug effects
  • Neurons / metabolism
  • Phosphorylation
  • Protein Tyrosine Phosphatase, Non-Receptor Type 1 / antagonists & inhibitors
  • Protein Tyrosine Phosphatase, Non-Receptor Type 1 / biosynthesis
  • Protein Tyrosine Phosphatase, Non-Receptor Type 1 / genetics
  • Protein Tyrosine Phosphatase, Non-Receptor Type 1 / metabolism*
  • Receptors, Erythropoietin / metabolism

Substances

  • Cytokine Receptor Common beta Subunit
  • Receptors, Erythropoietin
  • carbamylated erythropoietin
  • Erythropoietin
  • JAK2 protein, human
  • Janus Kinase 2
  • PTPN1 protein, human
  • Protein Tyrosine Phosphatase, Non-Receptor Type 1