Abstract
Rapid point-of-care (POC) diagnostic devices are needed for field-forward screening of severe acute systemic febrile illnesses. Multiplexed rapid lateral flow diagnostics have the potential to distinguish among multiple pathogens, thereby facilitating diagnosis and improving patient care. Here, we present a platform for multiplexed pathogen detection using multi-colored silver nanoplates. This design requires no external excitation source and permits multiplexed analysis in a single channel, facilitating integration and manufacturing.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, Non-P.H.S.
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Dengue Virus / isolation & purification*
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Ebolavirus / isolation & purification*
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Humans
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Immunoassay / instrumentation
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Limit of Detection
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Metal Nanoparticles / chemistry*
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Microfluidic Analytical Techniques / instrumentation*
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Point-of-Care Systems
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Silver / chemistry*
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Spectrum Analysis
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Virology / instrumentation*
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Virology / methods
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Virus Diseases / blood
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Virus Diseases / virology
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Yellow fever virus / isolation & purification*