Abstract
One new flavonoid, 5,6,7-trimethoxyflavone-8-O-β-D-glucopyranoside (1), along with six known compounds 2-7, was isolated from Oroxylum indicum. Their structures were determined on the basis of spectral data. The antibacterial activities of compounds 1-4 were studied. Compounds 1 and 3 showed medium antibacterial activity against Staphylococcus aureus with MIC/MBC at 32-128 μg/ml.
Keywords:
Oroxylum indicum; antibacterial activity; flavonoid.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Anti-Bacterial Agents / chemistry*
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Anti-Bacterial Agents / isolation & purification
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Bignoniaceae / chemistry*
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Flavones / chemistry
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Flavones / isolation & purification
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Flavonoids / chemistry*
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Flavonoids / isolation & purification
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Glucosides / chemistry
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Glucosides / isolation & purification
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Microbial Sensitivity Tests
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Molecular Structure
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Plant Bark / chemistry
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Plants, Medicinal / chemistry
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Staphylococcus aureus / drug effects
Substances
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5,6,7-trimethoxyflavone-8-O-glucopyranoside
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Anti-Bacterial Agents
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Flavones
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Flavonoids
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Glucosides