A case of solely lung-involved IgG4-related disease mimicking tuberculosis

Hongyi Tan; Haitao Li; Yongbing Hu; Ruichao Niu; Pinhua Pan; Chengping Hu

doi:10.1016/j.hrtlng.2014.12.005

A case of solely lung-involved IgG4-related disease mimicking tuberculosis

Heart Lung. 2015 Mar-Apr;44(2):161-4. doi: 10.1016/j.hrtlng.2014.12.005. Epub 2015 Feb 9.

Authors

Hongyi Tan¹, Haitao Li¹, Yongbing Hu², Ruichao Niu¹, Pinhua Pan³, Chengping Hu¹

Affiliations

¹ Pneumology Department, Xiangya Hospital, Central South University, Changsha 410008, China.
² Pathology Department, Xiangya Hospital, Central South University, Changsha 410008, China.
³ Pneumology Department, Xiangya Hospital, Central South University, Changsha 410008, China. Electronic address: [email protected].

PMID: 25676315
DOI: 10.1016/j.hrtlng.2014.12.005

Abstract

IgG4-related disease (IgG4-RD) is a chronic progressive autoimmune disease. Solely lung involved IgG4-RD is extremely rare. Herein, we reported a case of IgG4-related disease as mimicking tuberculosis. A 52-year-old male patient was admitted due to cough and hemoptysis for two months and fever for 1 month. The pre-admission diagnosis in another hospital was secondary pulmonary tuberculosis, but the quadruple anti-tuberculosis therapy was ineffective and the disease condition continued to deteriorate. The percutaneous lung biopsy was carried out after admission and the pathological diagnosis was IgG4-related disease. The patient's disease condition was improved following hormonal therapy.

Keywords: IgG4-related disease; Lung; Misdiagnosis; Solely invovled; Tuberculosis.

Publication types

Case Reports

MeSH terms

Fever / etiology
Hemoptysis / etiology
Hospitalization
Humans
Immunoglobulin G / blood*
Lung Diseases / diagnosis*
Male
Middle Aged
Tuberculosis, Pulmonary / diagnosis*

Substances

Immunoglobulin G