Implementing a simple care bundle is associated with improved outcomes in a national cohort of patients with ischemic stroke

Stroke. 2015 Apr;46(4):1065-70. doi: 10.1161/STROKEAHA.114.007608. Epub 2015 Feb 12.

Abstract

Background and purpose: Further research is needed to better identify the methods of evaluating processes and outcomes of stroke care. We investigated whether achieving 4 evidence-based components of a care bundle in a Scotland-wide population with ischemic stroke is associated with 30-day and 6-month outcomes.

Methods: Using national datasets, we looked at the effect of 4 standards (stroke unit entry on calendar day of admission [day 0] or day following [day 1], aspirin on day 0 or day 1, scan on day 0, and swallow screen recorded on day 0) on mortality and discharge to usual residence, at 30 days and 6 months. Data were corrected for the validated 6 simple variables, admission year, and hospital-level random effects.

Results: A total of 36,055 patients were included. Achieving stroke unit admission, swallow screen, and aspirin standards were associated with reduced 30-day mortality (adjusted odds ratio [95% confidence interval]: 0.82 [0.75-0.90], 0.88 [0.77-0.99], and 0.39 [0.35-0.43], respectively). Thirty-day all-cause mortality was higher when fewer standards were achieved, from 0 versus 4 (adjusted odds ratio [95% confidence interval], 2.95 [1.91-4.55]) to 3 versus 4 (adjusted odds ratio [95% confidence interval], 1.21 [1.09-1.34]). This effect persisted at 6 months. When less than the full care bundle was achieved, discharge to usual residence was less likely at 6 months (3 versus 4 standards; adjusted odds ratio [95% confidence interval], 0.91 [0.85-0.98]).

Conclusions: Achieving a care bundle for ischemic stroke is associated with reduced mortality at 30 days and 6 months and increased likelihood of discharge to usual residence at 6 months.

Keywords: patient outcome assessment; selection bias; standards; survival.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Aged, 80 and over
  • Brain Ischemia* / epidemiology
  • Brain Ischemia* / mortality
  • Brain Ischemia* / therapy
  • Cohort Studies
  • Humans
  • Male
  • Outcome Assessment, Health Care / statistics & numerical data*
  • Patient Care Bundles / methods
  • Patient Care Bundles / standards
  • Patient Care Bundles / statistics & numerical data*
  • Registries / statistics & numerical data*
  • Scotland / epidemiology
  • Stroke* / epidemiology
  • Stroke* / mortality
  • Stroke* / therapy
  • Treatment Outcome