[Linear tuberculoid leprosy along the lines of Blaschko: a very rare presentation]

Ann Dermatol Venereol. 2015 Apr;142(4):266-9. doi: 10.1016/j.annder.2015.01.005. Epub 2015 Feb 11.
[Article in French]

Abstract

Background: Leprosy continues to be present in certain regions throughout the world, and the dermatologist plays a central role in its diagnosis. Herein we report a case of tuberculoid leprosy that is atypical in terms of its linear presentation which appears to follow the lines of Blaschko.

Patients and methods: A patient from Mayotte was referred to the neurological department for suspected tuberculoid leprosy. He was presenting a deficiency of the ulnar nerve together with neuronal hypertrophy and cutaneous involvement. Dermatological examination revealed linear hypo-aesthetic hypopigmented lesions on the arm and forearm. The atypical clinical presentation also suggested to us pigmented mosaicism or post-inflammatory pigmentation. The biopsy showed granulomatous epithelial dermatitis with perinervous involvement. Imaging examinations confirmed the presence of neuronal hypertrophy. A diagnosis of linear tuberculoid leprosy was made.

Discussion: This case illustrates the need to bear in mind a diagnosis of leprosy in the event of hypopigmented lesions, even where they are linear and of Blaschkoid appearance. Several potential hypotheses may account for this particular topographical pattern.

Keywords: Blaschko; Blaschko lines; Dermatose linéaire; Hypopigmentation; Linear dermatitis; Lèpre tuberculoïde; Mosaïcisme; Tuberculoid leprosy.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Arm / pathology
  • Biopsy
  • Body Patterning*
  • Comoros / ethnology
  • Humans
  • Hypertrophy
  • Hypopigmentation / etiology
  • Leprosy, Tuberculoid / diagnosis*
  • Leprosy, Tuberculoid / pathology
  • Male
  • Tuberculoma / pathology
  • Ulnar Nerve / pathology
  • Ulnar Nerve / physiopathology
  • Young Adult