Tardive dyskinesia in schizophrenic patients: correlation with negative symptoms

Psychiatry Res. 1989 May;28(2):145-51. doi: 10.1016/0165-1781(89)90042-5.

Abstract

The relationship between severity of tardive dyskinesia (TD) and the prominence of negative symptoms was assessed in 25 right-handed, medicated schizophrenic patients. TD was quantified using ultrasound detectors and frequency measurement techniques as well as with observer rating scales. Electromechanical studies revealed a systematic relationship between TD severity and negative symptoms; TD was more severe in patients with fewer negative symptoms. The correlation was small in magnitude.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • Aged
  • Antipsychotic Agents / adverse effects
  • Attention / drug effects
  • Dyskinesia, Drug-Induced / psychology*
  • Humans
  • Middle Aged
  • Mood Disorders / psychology
  • Motivation / drug effects
  • Motor Activity / drug effects
  • Psychiatric Status Rating Scales
  • Risk Factors
  • Schizophrenia / drug therapy
  • Schizophrenic Psychology*

Substances

  • Antipsychotic Agents