RFLPs tightly linked with cystic fibrosis: value of probes at the D7S23 locus in prenatal diagnosis

F Vasseur; M Flactif; J B Savary; D Turpin; M M Deminatti

RFLPs tightly linked with cystic fibrosis: value of probes at the D7S23 locus in prenatal diagnosis

Ann Genet. 1989;32(2):78-81.

Authors

F Vasseur¹, M Flactif, J B Savary, D Turpin, M M Deminatti

Affiliation

¹ Service de Génétique, Faculté de Médecine, Lille, France.

PMID: 2569290

Abstract

In a 1:4 risk family, the usefulness of probes at the D7S23 locus for prenatal diagnosis of cystic fibrosis is discussed by comparison with probes at the MET, D7S8, and D7S18 loci that did not allow accuracy in this family.

MeSH terms

Cystic Fibrosis / diagnosis
Cystic Fibrosis / genetics*
Female
Fetal Diseases / diagnosis
Fetal Diseases / genetics*
Genetic Linkage*
Genetic Markers
Haplotypes*
Humans
Polymorphism, Genetic*
Polymorphism, Restriction Fragment Length*
Pregnancy
Prenatal Diagnosis / methods*

Substances

Genetic Markers