Successful treatment with glucocorticoid for secondary Fanconi syndrome caused by sarcoidosis

Mod Rheumatol. 2017 May;27(3):545-547. doi: 10.3109/14397595.2014.1002163. Epub 2015 Jul 29.

Abstract

A 77-year-old female with renal dysfunction, hypercalcemia, and hypercalciuria was presented. Systemic investigations including renal biopsy showed that the patient had Fanconi syndrome secondary to renal sarcoidosis. Treatment with 25 mg per day of prednisolone was initiated and her condition improved. Complication of Fanconi syndrome in patients with sarcoidosis is extremely rare. Although the pathological mechanism is still unknown, corticosteroid therapy was effective for ameliorating proteinuria, glycosuria, hypercalciuria, and aminoaciduria.

Keywords: Corticosteroid; Fanconi syndrome; Hypercalcemia; Sarcoidosis.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Anti-Inflammatory Agents / administration & dosage
  • Anti-Inflammatory Agents / therapeutic use*
  • Fanconi Syndrome / diagnosis
  • Fanconi Syndrome / drug therapy*
  • Fanconi Syndrome / etiology
  • Female
  • Glucocorticoids / administration & dosage
  • Glucocorticoids / therapeutic use*
  • Humans
  • Prednisolone / administration & dosage
  • Prednisolone / therapeutic use*
  • Sarcoidosis / complications*
  • Sarcoidosis / diagnosis
  • Sarcoidosis / drug therapy

Substances

  • Anti-Inflammatory Agents
  • Glucocorticoids
  • Prednisolone