Imaging areas of retinal nonperfusion in ischemic branch retinal vein occlusion with swept-source OCT microangiography

Ophthalmic Surg Lasers Imaging Retina. 2015 Feb;46(2):249-52. doi: 10.3928/23258160-20150213-19.

Abstract

The authors present the case of a patient with a history of ischemic branch vein occlusion and multimodal imaging of the retinal vasculature by fluorescein angiography (FA) and ultrahigh-speed swept-source optical coherence tomography (SS-OCT) microangiography (SS-OCT laser prototype; 1,050 nm, 100,000 A-scans/second). Multiple images across the macula were acquired (3 × 3 mm cubes in clusters of four repeated B-scans). En face images of the vasculature were generated by implementing an intensity differentiation algorithm. The retinal vasculature as well areas of nonperfusion could be identified precisely at multiple retinal levels. Ultrahigh-speed SS-OCT microangiography provides noninvasive, three-dimensional, high-resolution images of the retinal vasculature including the capillaries.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Angiogenesis Inhibitors / therapeutic use
  • Cataract Extraction
  • Female
  • Fluorescein Angiography*
  • Humans
  • Imaging, Three-Dimensional
  • Ischemia / diagnosis*
  • Ischemia / physiopathology
  • Ischemia / therapy
  • Laser Coagulation
  • Microcirculation
  • Multimodal Imaging
  • Regional Blood Flow
  • Retinal Vein Occlusion / diagnosis*
  • Retinal Vein Occlusion / physiopathology
  • Retinal Vein Occlusion / therapy
  • Retinal Vessels / pathology*
  • Tomography, Optical Coherence*
  • Vascular Endothelial Growth Factor A / antagonists & inhibitors
  • Visual Acuity

Substances

  • Angiogenesis Inhibitors
  • VEGFA protein, human
  • Vascular Endothelial Growth Factor A