Abstract
In this review the data on consolidation and reconsolidation of memory by its reactivation (reminding) by a conditional stimulus or context are presented. A special attention is paid to "time windows" when amnesic and other interventions during memory reconsolidation become effective. The similarities and differences between consolidation of original learning and repeated consolidation (reconsolidation) during reactivation of memory by a conditional stimulus or context are considered. The hypotheses about memory updating during reconsolidation and some possible ways affecting memory are also discussed.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Amnesia / physiopathology
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Brain-Derived Neurotrophic Factor / genetics
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Brain-Derived Neurotrophic Factor / metabolism
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Conditioning, Psychological / physiology
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Early Growth Response Protein 1 / genetics
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Early Growth Response Protein 1 / metabolism
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Gene Expression Regulation / physiology*
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Humans
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Memory, Long-Term / physiology*
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Memory, Short-Term / physiology*
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Mental Recall / physiology*
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Protein Kinase C / genetics
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Protein Kinase C / metabolism
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Receptors, Adrenergic, beta / genetics
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Receptors, Adrenergic, beta / metabolism
Substances
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Brain-Derived Neurotrophic Factor
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EGR1 protein, human
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Early Growth Response Protein 1
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Receptors, Adrenergic, beta
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BDNF protein, human
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protein kinase C zeta
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Protein Kinase C