Manganese catalysed sulfenylation of N-methyl amides with arenesulfonyl hydrazides

Org Biomol Chem. 2015 Apr 7;13(13):3878-81. doi: 10.1039/c5ob00133a.

Abstract

A convenient oxidative sulfenylation method for the formation of various sulfenyl amides has been reported. Arenesulfonyl hydrazine as a sulfur source in the presence of a manganese salt can activate the sp(3) C-H bond of N-methyl amides through a free-radical pathway using di-tert-butyl peroxide (DTBP).

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amides / chemistry*
  • Catalysis
  • Hydrazines / chemistry*
  • Hydrocarbons, Aromatic / chemistry*
  • Manganese / chemistry*
  • Sulfonic Acids / chemistry*

Substances

  • Amides
  • Hydrazines
  • Hydrocarbons, Aromatic
  • Sulfonic Acids
  • hydrazine
  • Manganese