Effect of a Vietnamese Cinnamomum cassia essential oil and its major component trans-cinnamaldehyde on the cell viability, membrane integrity, membrane fluidity, and proton motive force of Listeria innocua

Can J Microbiol. 2015 Apr;61(4):263-71. doi: 10.1139/cjm-2014-0481. Epub 2015 Jan 13.

Abstract

The antibacterial mechanism of a Cinnamomum cassia essential oil from Vietnam and of its main component (trans-cinnamaldehyde, 90% (m/m) of C. cassia essential oil) against a Listeria innocua strain was investigated to estimate their potential for food preservation. In the presence of C. cassia essential oil or trans-cinnamaldehyde at their minimal bactericidal concentration (2700 μg·mL(-1)), L. innocua cells fluoresced green after staining with Syto9® and propidium iodide, as observed by epifluorescence microscopy, suggesting that the perturbation of membrane did not cause large pore formation and cell lysis but may have introduced the presence of viable but nonculturable bacteria. Moreover, the fluidity, potential, and intracellular pH of the cytoplasmic membrane were perturbed in the presence of the essential oil or trans-cinnamaldehyde. However, these membrane perturbations were less severe in the presence of trans-cinnamaldehyde than in the presence of multicomponent C. cassia essential oil. This indicates that in addition to trans-cinnamaldehyde, other minor C. cassia essential oil components play a major role in its antibacterial activity against L. innocua cells.

Keywords: Cinnamomum cassia essential oil; activité antibactérienne; antibacterial activity; fluidité membranaire; force proton motrice; huile essentielle de Cinnamomum cassia; intégrité membranaire; membrane fluidity; membrane integrity; proton motive force.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acrolein / analogs & derivatives*
  • Acrolein / chemistry
  • Acrolein / pharmacology
  • Anti-Bacterial Agents / chemistry
  • Anti-Bacterial Agents / pharmacology*
  • Cell Membrane / chemistry
  • Cell Membrane / drug effects
  • Cell Membrane / metabolism
  • Cinnamomum / chemistry*
  • Listeria / chemistry
  • Listeria / drug effects*
  • Listeria / growth & development
  • Listeria / metabolism
  • Membrane Fluidity / drug effects
  • Microbial Viability / drug effects
  • Oils, Volatile / chemistry
  • Oils, Volatile / pharmacology*
  • Plant Extracts / chemistry
  • Plant Extracts / pharmacology*
  • Proton-Motive Force / drug effects

Substances

  • Anti-Bacterial Agents
  • Oils, Volatile
  • Plant Extracts
  • Acrolein
  • cinnamaldehyde